A macule is a flat, distinct, discolored area of skin that is usually less than 1 centimeter wide. It usually does not include a change in skin texture or thickness.
Habif TP, ed. Principles of diagnosis and anatomy. Clinical Dermatology. 5th ed. St. Louis, Mo: Mosby Elsevier; 2009:chap 1.
David C. Dugdale, III, MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine. Also reviewed by A.D.A.M. Health Solutions, Ebix, Inc., Editorial Team: David Zieve, MD, MHA, David R. Eltz, Stephanie Slon, and Nissi Wang.